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    Breakthrough Device Heals Organs with a Single Touch - Astonishing!

    Carol
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    Post  Carol Sat Aug 12, 2017 2:58 pm


    https://www.youtube.com/watch?v=tMQ51Kj2tS0&feature=youtu.be
    Breakthrough Device Heals Organs with a Single Touch

    Uploaded on Aug 3, 2017
    (COLUMBUS, Ohio) – Researchers have developed a device that can switch cell function to rescue failing body functions with a single touch. The technology, known as Tissue Nanotransfection (TNT), injects genetic code into skin cells, turning those skin cells into other types of cells required for treating diseased conditions. “It takes just a fraction of a second. You simply touch the chip to the wounded area, then remove it,” said Chandan Sen, PhD, director of the Center for Regenerative Medicine and Cell-Based Therapies at The Ohio State University Wexner Medical Center. “At that point, the cell reprogramming begins.” In a series of lab tests, researchers applied the chip to the injured legs of mice that vascular scans showed had little to no blood flow. “We reprogrammed their skin cells to become vascular cells,” Sen said. “Within a week we began noticing the transformation.” By the second week, active blood vessels had formed, and by the third week, the legs of the mice were saved—with no other form of treatment. “It extends the concept known as gene therapy, and it has been around for quite some time,” said study collaborator James Lee, PhD, a professor of chemical and biomolecular engineering at Ohio State. “The difference with our technology is how we deliver the DNA into the cells.” The chip, loaded with specific genetic code or certain proteins, is placed on the skin, and a small electrical current creates channels in the tissue. The DNA or RNA is injected into those channels where it takes root and begins to reprogram the cells. In a new study published in Nature Nanotechnology, first author Daniel Gallego-Perez of Ohio State demonstrated that the technique worked with up to 98 percent efficiently. “What’s even more exciting is that it not only works on the skin, but on any type of tissue,” Sen said. In fact, researchers were able to grow brain cells on the skin surface of a mouse, harvest them, then inject them into the mouse’s injured brain. Just a few weeks after having a stroke, brain function in the mouse was restored, and it was healed. Because the technique uses a patient’s own cells and does not rely on medication, researchers expect it to be approved for human trials within a year.


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    With deepest respect ~ Aloha & Mahalo, Carol
    Carol
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    Post  Carol Sat Aug 12, 2017 3:06 pm



    _________________
    What is life?
    It is the flash of a firefly in the night, the breath of a buffalo in the wintertime. It is the little shadow which runs across the grass and loses itself in the sunset.

    With deepest respect ~ Aloha & Mahalo, Carol
    Swanny
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    Post  Swanny Sat Aug 12, 2017 3:07 pm

    That will obviously disappear, only to be used by the elite
    Carol
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    Post  Carol Sat Aug 12, 2017 3:22 pm

    Breakthrough Device Heals Organs with a Single Touch - Astonishing! Nanochip-on-arm_1024
    http://www.sciencealert.com/new-nanochip-devices-could-heal-organs-with-a-single-touch
    This Insane Nanochip Device Can Heal Tissue Just by Touching The Skin Once

    Wait, are we in Star Trek now?
    DAVID NIELD 9 AUG 2017

    Imagine buzzing the skin over an internal wound with an electrical device and having it heal over just a few days – that's the promise of new nanochip technology that can reprogram cells to replace tissue or even whole organs.

    It's called Tissue Nanotransfection (TNT), and while it's only been tested on mice and pigs so far, the early signs are encouraging for this new body repair tool - and it sounds like a device straight out of science-fiction.

    The prototype device, developed by a team at Ohio State University, sits on the skin and uses an intense electrical field to deliver specific genes to the tissue underneath it. Those genes create new types of cells that can be used nearby or elsewhere in the body.

    "By using our novel nanochip technology, injured or compromised organs can be replaced," says one of the study leaders, Chandan Sen. "We have shown that skin is a fertile land where we can grow the elements of any organ that is declining."

    During animal tests, researchers were able to use TNT to reprogram skin cells on the outside of injured legs to become vascular cells, which are key to regulating a healthy blood flow through the body.

    Within a week, active blood vessels appeared in the injured legs, and by the second week the injured legs had been saved by TNT.

    What's more, nerve cells generated in the lab using the same technique were used to successfully help brain-injured mice recover from a stroke.

    "This is difficult to imagine, but it is achievable, successfully working about 98 percent of the time," says Sen. "With this technology, we can convert skin cells into elements of any organ with just one touch."

    Other scientists are already investigating ways of reprogramming cells to repair the body, but what makes this particular technique stand out is that it skips the usual intermediary step of creating pluripotent stem cells, cells that can then turn into any other cell type.

    In this case the cells go straight from skin cells to another variety of cell, all thanks to the targeted release of genes and an electrical pulse.

    The TNT technology is made up of two components: the nanotechnology-based chip that sits on the skin, about the size of a cufflink, and the biological cargo it contains to affect the tissue underneath.

    The chip gets zapped with a harmless electrical charge to release the cargo into the cell membranes, and the chip can then be removed.

    According to the researchers it all takes less than a second to apply. The process is non-invasive, and because the reprogrammed cells are already in the patient's body, immune suppression is not required to make sure the new tissue is accepted.

    We should note that there's still a long way to go before we could use this process on our own bodies, but the researchers are continuing to refine the technique and work towards human trials sometime next year.

    "The concept is very simple," says one of the researchers, L. James Lee. "As a matter of fact, we were even surprised how it worked so well."

    "In my lab, we have ongoing research trying to understand the mechanism and do even better. So, this is the beginning, more to come."

    The research has been published in Nature Nanotechnology.




    _________________
    What is life?
    It is the flash of a firefly in the night, the breath of a buffalo in the wintertime. It is the little shadow which runs across the grass and loses itself in the sunset.

    With deepest respect ~ Aloha & Mahalo, Carol
    Carol
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    Post  Carol Sat Aug 12, 2017 3:24 pm

    PUBLIC RELEASE: 7-AUG-2017
    Breakthrough device heals organs with a single touch
    Device instantly delivers new DNA or RNA into living skin cells to change their function

    OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER

    https://eurekalert.org/pub_releases/2017-08/m-bdh080317.php

    VIDEO: DEVICE INSTANTLY DELIVERS NEW DNA OR RNA INTO LIVING SKIN CELLS TO CHANGE THEIR FUNCTION. view more

    CREDIT: PLEASE COURTESY THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER.


    Researchers at The Ohio State University Wexner Medical Center and Ohio State's College of Engineering have developed a new technology, Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient's own body. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells.

    Results of the regenerative medicine study published in the journal Nature Nanotechnology.

    "By using our novel nanochip technology, injured or compromised organs can be replaced. We have shown that skin is a fertile land where we can grow the elements of any organ that is declining," said Dr. Chandan Sen, director of Ohio State's Center for Regenerative Medicine & Cell Based Therapies, who co-led the study with L. James Lee, professor of chemical and biomolecular engineering with Ohio State's College of Engineering in collaboration with Ohio State's Nanoscale Science and Engineering Center.

    Researchers studied mice and pigs in these experiments. In the study, researchers were able to reprogram skin cells to become vascular cells in badly injured legs that lacked blood flow. Within one week, active blood vessels appeared in the injured leg, and by the second week, the leg was saved. In lab tests, this technology was also shown to reprogram skin cells in the live body into nerve cells that were injected into brain-injured mice to help them recover from stroke.

    "This is difficult to imagine, but it is achievable, successfully working about 98 percent of the time. With this technology, we can convert skin cells into elements of any organ with just one touch. This process only takes less than a second and is non-invasive, and then you're off. The chip does not stay with you, and the reprogramming of the cell starts. Our technology keeps the cells in the body under immune surveillance, so immune suppression is not necessary," said Sen, who also is executive director of Ohio State's Comprehensive Wound Center.

    TNT technology has two major components: First is a nanotechnology-based chip designed to deliver cargo to adult cells in the live body. Second is the design of specific biological cargo for cell conversion. This cargo, when delivered using the chip, converts an adult cell from one type to another, said first author Daniel Gallego-Perez, an assistant professor of biomedical engineering and general surgery who also was a postdoctoral researcher in both Sen's and Lee's laboratories.

    TNT doesn't require any laboratory-based procedures and may be implemented at the point of care. The procedure is also non-invasive. The cargo is delivered by zapping the device with a small electrical charge that's barely felt by the patient.

    "The concept is very simple," Lee said. "As a matter of fact, we were even surprised how it worked so well. In my lab, we have ongoing research trying to understand the mechanism and do even better. So, this is the beginning, more to come."

    Researchers plan to start clinical trials next year to test this technology in humans, Sen said.

    ###

    Funding for this research was provided by Leslie and Abigail Wexner, Ohio State's Center for Regenerative Medicine and Cell-Based Therapies and Ohio State's Nanoscale Science and Engineering Center.


    _________________
    What is life?
    It is the flash of a firefly in the night, the breath of a buffalo in the wintertime. It is the little shadow which runs across the grass and loses itself in the sunset.

    With deepest respect ~ Aloha & Mahalo, Carol
    Carol
    Carol
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    Post  Carol Sat Aug 12, 2017 3:28 pm

    "As a healthcare provider who has been in both the OR & ICU settings, I assure you this would be a miracle for many...  However, it sure seems to be an extreme jump over technology...

    So, while the nano chip technology is exciting, I am skeptical of the end game of the technology. Unfortunately, changing cell composition "for good" today can easily be "for evil" in the future...

    If you have not done any research on transhumanism then it is something that all need to understand- this will be the evolution of the human if the PTB have anything to say about it and we know they will.  It is my opinion they are not going away."


    2045: A New Era for Humanity

    https://youtu.be/01hbkh4hXEk

    There is no doubt in my mind that this is the direction of humanity and the evolution of the human.  IMO - once you allow the downloading of your brain, you have just lost your soul.

    Finally, the following 7 min video provides a nice overview of the above Russian initiative and the moral & ethical questions we should be asking ourselves about transhumanism.  Worth watching...


    Transhumanism & 2045 Initiative - The Age of Digital Immortality

    https://youtu.be/wC1vxdyoHzU


    _________________
    What is life?
    It is the flash of a firefly in the night, the breath of a buffalo in the wintertime. It is the little shadow which runs across the grass and loses itself in the sunset.

    With deepest respect ~ Aloha & Mahalo, Carol
    Swanny
    Swanny


    Posts : 1185
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    Post  Swanny Sun Aug 13, 2017 2:25 am


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