'Matrix'-Style Effortless Learning? Vision Scientists Demonstrate Innovative Learning Method

ScienceDaily (Dec. 12, 2011) — New research published December 8 in the journal Science suggests it may be possible to use brain technology to learn to play a piano, reduce mental stress or hit a curve ball with little or no conscious effort. It's the kind of thing seen in Hollywood's "Matrix" franchise. In the future, a person may be able to watch a computer screen and have his or her brain patterns modified to improve physical or mental performance. Researchers say an innovative learning method that uses decoded functional magnetic resonance imaging could modify brain activities to help people recuperate from an accident or disease, learn a new language or even fly a plane. (Credit: Nicolle Rager Fuller, NSF) read more at link.

ScienceDaily (May 3, 2010) — Stress, sickness and depression can generate inflammation in the brain, which is detrimental to learning. According to a new study that will appear online on May 3rd in the Journal of Experimental Medicine, T cells level the learning curve by producing a protein that combats inflammation, establishing a more learning-conducive environment in the brain. Learning defects had been reported in mice lacking T cells, but how these cells boosted brain power was unknown. A team led by Jonathan Kipnis (University of Virginia, Charlottesville) investigated the activity of these cells in mice trained to find their way through a water maze. Training the mice caused T cells to accumulate in the membrane that surrounds the brain. Once there, the cells produced a protein called interleukin-4 (IL-4), which reduced the abundance of inflammatory proteins known to hinder learning. Mice lacking IL-4 had a hard time navigating the maze, but their learning disability could be reversed by giving them IL-4-producing T cells.

It's not yet clear if IL-4 has similar effects in humans. If so, these findings could impact the design of new therapies aimed at boosting learning and memory in children with learning disabilities or adults with age-related dementia.

ScienceDaily (May 2, 2011) — A new protein, called aquaporin-4, is making waves and found to play a key role in brain inflammation, or encephalitis. This discovery is important as the first to identify a role for this protein in inflammation, opening doors for the development of new drugs that treat brain inflammation and other conditions at the cellular level rather than just treating the symptoms. "Our study establishes a novel role for a water channel, aquaporin-4, in neuroinflammation, as well as a cell-level mechanism," said Alan S. Verkman, M.D., Ph.D., a senior researcher involved in the work from the Department of Medicine and the Department of Physiology at the University of California, San Francisco. "Our data suggest that inhibition or down-regulation of aquaporin-4 expression in brain and spinal cord may offer a new therapeutic option in diseases such as multiple sclerosis, neuromyelitis optica and other conditions associated with neuroinflammation." more at link

This is interesting.


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